Loss of c‐Kit function impairs arteriogenesis in a mouse model of hindlimb ischemia
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DOI: 10.1016/j.surg.2017.10.052
Abstract: Background. Arteriogenesis is a process whereby collateral vessels remodel usually in response to increased blood flow and/or wall stress. Remodeling of collaterals can function as a natural bypass to alleviate ischemia during arterial occlusion. Here… read more here.
Keywords: recovery; hindlimb ischemia; arteriogenesis; kit ... See more keywords
Endothelial Hyaluronan Synthase 3 Augments Postischemic Arteriogenesis Through CD44/eNOS Signaling
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DOI: 10.1161/atvbaha.121.315478
Abstract: Supplemental Digital Content is available in the text. Objective: The dominant driver of arteriogenesis is elevated shear stress sensed by the endothelial glycocalyx thereby promoting arterial outward remodeling. Hyaluronan, a critical component of the endothelial… read more here.
Keywords: has3; arteriogenesis; cd44; hyaluronan ... See more keywords
Ischemic-Trained Monocytes Improve Arteriogenesis in a Mouse Model of Hindlimb Ischemia
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DOI: 10.1161/atvbaha.121.317197
Abstract: Supplemental Digital Content is available in the text. Objective: Monocytes, which play an important role in arteriogenesis, can build immunologic memory by a functional reprogramming that modifies their response to a second challenge. This process,… read more here.
Keywords: arteriogenesis; trained monocytes; ischemic trained; hindlimb ischemia ... See more keywords
Notch Signaling-Modified Mesenchymal Stem Cell Patch Improves Left Ventricular Function via Arteriogenesis Induction in a Rat Myocardial Infarction Model
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DOI: 10.1177/09636897231154580
Abstract: For ischemic cardiomyopathy (ICM) with limited therapeutic options, the induction of arteriogenesis has the potential to improve cardiac function through major restoration of blood flow. We hypothesized that transplantation of a Notch signaling-modified mesenchymal stem… read more here.
Keywords: cell; function; arteriogenesis; cell patch ... See more keywords
Structural Remodeling of the Extracellular Matrix in Arteriogenesis: A Review
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DOI: 10.3389/fcvm.2021.761007
Abstract: Lower extremity arterial occlusive disease (AOD) results in significant morbidity and mortality for the population, with up to 10% of patients ultimately requiring amputation. An alternative method for non-surgical revascularization which is yet to be… read more here.
Keywords: extracellular matrix; matrix; arteriogenesis; remodeling extracellular ... See more keywords
The Extraordinary Role of Extracellular RNA in Arteriogenesis, the Growth of Collateral Arteries
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DOI: 10.3390/ijms20246177
Abstract: Arteriogenesis is an intricate process in which increased shear stress in pre-existing arteriolar collaterals induces blood vessel expansion, mediated via endothelial cell activation, leukocyte recruitment and subsequent endothelial and smooth muscle cell proliferation. Extracellular RNA… read more here.
Keywords: shear stress; arteriogenesis; extraordinary role; growth ... See more keywords
Cobra Venom Factor Boosts Arteriogenesis in Mice
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DOI: 10.3390/ijms23158454
Abstract: Arteriogenesis, the growth of natural bypass blood vessels, can compensate for the loss of arteries caused by vascular occlusive diseases. Accordingly, it is a major goal to identify the drugs promoting this innate immune system-driven… read more here.
Keywords: factor boosts; venom factor; arteriogenesis; cobra venom ... See more keywords
Tongxinluo promotes endothelium-dependent arteriogenesis to attenuate diabetic peripheral arterial disease
Sign Up to like & getrecommendations! Published in 2023 at "World Journal of Diabetes"
DOI: 10.4239/wjd.v14.i3.234
Abstract: BACKGROUND Peripheral arterial disease (PAD) has become one of the leading causes of disa-bility and death in diabetic patients. Restoring blood supply to the hindlimbs, especially by promoting arteriogenesis, is currently the most effective strategy,… read more here.
Keywords: txl; cell; arteriogenesis; disease ... See more keywords