Human umbilical artery endothelial cells from Large‐for‐Gestational‐Age newborn have increased antioxidant efficiency and gene expression
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28494
Abstract: Obesity is a public health problem worldwide, and especially in women in reproductive age where more than one in three have obesity. Maternal obesity is associated with an increased maternal, placental, and newborn oxidative stress,… read more here.
Keywords: large gestational; age; human umbilical; gestational age ... See more keywords
Human pulmonary artery endothelial cells upregulate ACE2 expression in response to iron‐regulatory elements: potential implications for SARS‐CoV‐2 infection
Sign Up to like & getrecommendations! Published in 2022 at "Pulmonary Circulation"
DOI: 10.1002/pul2.12068
Abstract: Vascular endothelial cell dysfunction is reported in severe COVID-19 disease, however controversy exists regarding levels of ACE2 expression, a coreceptor for SarsCov2, in these cells. We report ACE2 expression and positive regulation by both IL-6,… read more here.
Keywords: pulmonary artery; ace2 expression; potential implications; artery endothelial ... See more keywords
8-Chloroadenosine induces apoptosis in human coronary artery endothelial cells through the activation of the unfolded protein response
Sign Up to like & getrecommendations! Published in 2019 at "Redox Biology"
DOI: 10.1016/j.redox.2019.101274
Abstract: Infiltration of leukocytes within the vessel at sites of inflammation and the subsequent generation of myeloperoxidase-derived oxidants, including hypochlorous acid, are key characteristics of atherosclerosis. Hypochlorous acid is a potent oxidant that reacts readily with… read more here.
Keywords: unfolded protein; activation unfolded; coronary artery; endothelial cells ... See more keywords
Gremlin-1 is a key regulator of endothelial-to-mesenchymal transition in human pulmonary artery endothelial cells.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2020.111941
Abstract: BACKGROUND Endothelial-to-mesenchymal transition (EndMT) has been implicated in initiation and progression of pulmonary arterial hypertension (PAH). Gremlin-1 promotes vascular remodeling of PAH and mediates epithelial-mesenchymal transition, which is similar to EndMT. In the present study… read more here.
Keywords: mesenchymal transition; endothelial mesenchymal; gremlin; pulmonary artery ... See more keywords
Upregulation of Endothelial DKK1 (Dickkopf 1) Promotes the Development of Pulmonary Hypertension Through the Sp1 (Specificity Protein 1)/SHMT2 (Serine Hydroxymethyltransferase 2) Pathway
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DOI: 10.1161/hypertensionaha.121.18672
Abstract: Background: Pulmonary hypertension (PH) is a cancer-like proliferative disease, which has no curative treatment options. The dysfunction of pulmonary artery endothelial cells plays a key role in PH. DKK1 (Dickkopf 1) is a secretory glycoprotein… read more here.
Keywords: pulmonary hypertension; endothelial cells; pulmonary artery; artery endothelial ... See more keywords
Pequi Fruit Extract Increases Antioxidant Enzymes and Reduces Oxidants in Human Coronary Artery Endothelial Cells
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11030474
Abstract: Reactive oxygen species (ROS) imbalance results in endothelial cell function impairment. Natural phenolic antioxidant compounds have been investigated as therapeutic alternatives. The fruit bark of Brazilian-native pequi (Caryocar brasiliense, Camb.) is rich in polyphenols. The… read more here.
Keywords: coronary artery; extract; human coronary; artery endothelial ... See more keywords
LncRNA GAS5 promotes spermidine-induced autophagy through the miRNA-31-5p/NAT8L axis in pulmonary artery endothelial cells of patients with CTEPH
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2022.12813
Abstract: Chronic thromboembolic pulmonary hypertension (CTEPH) is a leading cause of pulmonary hypertension. The present study investigated the mechanisms of long non-coding RNA growth arrest-specific transcript 5 (GAS5) on spermidine (SP)-induced autophagy. Pulmonary artery endothelial cells… read more here.
Keywords: gas5; induced autophagy; pulmonary artery; artery endothelial ... See more keywords