Recent Advances in “Functional Engineering of Articular Cartilage Zones by Polymeric Biomaterials Mediated with Physical, Mechanical, and Biological/Chemical Cues”
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202581
Abstract: Articular cartilage (AC) plays an unquestionable role in joint movements but unfortunately the healing capacity is restricted due to its avascular and acellular nature. While cartilage tissue engineering has been lifesaving, it is very challenging… read more here.
Keywords: cartilage; articular cartilage; engineering; biological chemical ... See more keywords
Articular Cartilage‐Inspired Surface Functionalization for Enhanced Lubrication
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DOI: 10.1002/admi.201900180
Abstract: Natural articular cartilage has excellent superlubrication property, and it is attributed to the hydration lubrication mechanism of the charged biomacromolecules which extend from the cartilage surface to form a brush‐like layer. In this study, a… read more here.
Keywords: lubrication; articular cartilage; spectroscopy; surface ... See more keywords
Changes in endogenous UV fluorescence and biomechanical stiffness of bovine articular cartilage after collagenase digestion are strongly correlated.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biophotonics"
DOI: 10.1002/jbio.201600093
Abstract: A significant source of morbidity in the elderly population of the United States is osteoarthritis (OA), a disease caused by the breakdown and loss of articular cartilage. The exact causes of OA remain unknown, though… read more here.
Keywords: endogenous fluorescence; collagenase; articular cartilage; digestion ... See more keywords
Intrinsic fluorescence and mechanical testing of articular cartilage in human patients with osteoarthritis.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of biophotonics"
DOI: 10.1002/jbio.201600269
Abstract: The degeneration of articular cartilage is the main cause of osteoarthritis (OA), a common cause of disability among elderly patients. The aim of this study is to understand the correlation between intrinsic fluorescence of articular… read more here.
Keywords: patients osteoarthritis; fluorescence; articular cartilage; excitation ... See more keywords
Primary Cilia Direct Murine Articular Cartilage Tidemark Patterning Through Hedgehog Signaling and Ambulatory Load
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4506
Abstract: Articular cartilage (AC) is essential for body movement but is highly susceptible to degenerative diseases and has poor self‐repair capacity. To improve current subpar regenerative treatments, developmental mechanisms of AC should be clarified and, specifically,… read more here.
Keywords: hedgehog signaling; tidemark; tidemark patterning; load ... See more keywords
IGF‐1 and BMP‐7 synergistically stimulate articular cartilage repairing in the rabbit knees by improving chondrogenic differentiation of bone‐marrow mesenchymal stem cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27841
Abstract: Knee injury is known as a frequently occurred damage related to sports, which may affect the function of cartilage. This study aims to explore whether Insulin‐like growth factor 1 (IGF‐1) and bone morphogenetic protein‐7 (BMP‐7)‐modified… read more here.
Keywords: bmp; igf bmp; articular cartilage; damage ... See more keywords
Reduced PDGF‐AA in subchondral bone leads to articular cartilage degeneration after strenuous running
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28427
Abstract: To identify the effects of running on articular cartilage and subchondral bone remodeling, C57BL/6 mice were randomly divided into three groups: control, moderate‐, and strenuous running. Magnetic resonance imaging showed bone marrow lesions in the… read more here.
Keywords: pdgf subchondral; strenuous running; articular cartilage; subchondral bone ... See more keywords
Elevated adiabatic T1ρ and T2ρ in articular cartilage are associated with cartilage and bone lesions in early osteoarthritis: A preliminary study
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.25616
Abstract: To evaluate adiabatic T1ρ and T2ρ of articular cartilage in symptomatic osteoarthritis (OA) patients and asymptomatic volunteers, and to determine their association with magnetic resonance imaging (MRI)‐based structural abnormalities in cartilage and bone. read more here.
Keywords: elevated adiabatic; articular cartilage; cartilage bone; adiabatic articular ... See more keywords
Quantitative susceptibility mapping of articular cartilage in patients with osteoarthritis at 3T
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.26535
Abstract: Quantitative susceptibility mapping (QSM) has recently been applied in humans to quantify the magnetic susceptibility of collagen fibrils in the articular cartilage. read more here.
Keywords: mapping articular; susceptibility; articular cartilage; susceptibility mapping ... See more keywords
Machine Learning Prediction of Collagen Fiber Orientation and Proteoglycan Content From Multiparametric Quantitative MRI in Articular Cartilage
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.28353
Abstract: Machine learning models trained with multiparametric quantitative MRIs (qMRIs) have the potential to provide valuable information about the structural composition of articular cartilage. read more here.
Keywords: learning prediction; machine learning; articular cartilage; multiparametric quantitative ... See more keywords
Evaluation of articular cartilage with quantitative MRI in an equine model of post‐traumatic osteoarthritis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Orthopaedic Research"
DOI: 10.1002/jor.24780
Abstract: Chondral lesions lead to degenerative changes in the surrounding cartilage tissue, increasing the risk of developing post‐traumatic osteoarthritis (PTOA). This study aimed to investigate the feasibility of quantitative magnetic resonance imaging (qMRI) for evaluation of… read more here.
Keywords: post traumatic; traumatic osteoarthritis; articular cartilage; evaluation articular ... See more keywords