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   Articles with "artificial enzymes" as a keyword



Framework Nucleic Acid-Enabled Programming of Electrochemical Catalytic Properties of Artificial Enzymes.

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recommendations! Published in 2019 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.9b06480

Abstract: The creation and engineering of artificial enzymes remain a challenge, especially the arrangement of enzymes into geometric patterns with nanometer precision. In this work, we fabricated a series of novel DNA-tetrahedron-scaffolded-DNAzymes (Tetrazymes) and evaluated the… read more here.

Keywords: artificial enzymes; framework nucleic; programming electrochemical; acid enabled ... See more keywords

Efficient Cytosolic Delivery of Single-Chain Polymeric Artificial Enzymes for Intracellular Catalysis and Chemo-Dynamic Therapy.

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recommendations! Published in 2024 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.4c14264

Abstract: Designing artificial enzymes for in vivo catalysis presents a great challenge due to biomacromolecule contamination, poor biodistribution, and insufficient substrate interaction. Herein, we developed single-chain polymeric nanoparticles with Cu/N-heterocyclic carbene active sites (SCNP-Cu) to function… read more here.

Keywords: catalysis chemo; artificial enzymes; single chain; chain polymeric ... See more keywords

Chirality-Driven Metal-Phenolic Artificial Enzymes Enable Renal Targeting and Antioxidative Therapy Enhancement for Acute Kidney Injury.

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recommendations! Published in 2025 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.5c12337

Abstract: Despite advancements in artificial enzymes (AEs) for acute kidney injury (AKI) therapy through renal redox homeostasis modulation, the trade-off between organ-specific targeting and high multienzyme-mimicking catalytic efficiency is still a big challenge. Herein, we address… read more here.

Keywords: artificial enzymes; therapy; chirality; kidney injury ... See more keywords

Conceptual similarities between zeolites and artificial enzymes† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc02477h

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recommendations! Published in 2019 at "Chemical Science"

DOI: 10.1039/c9sc02477h

Abstract: Inspired by artificial enzymes, we have designed zeolites acting as scaffolds for a given Diels–Alder reaction using mimics of the reaction transition state. read more here.

Keywords: similarities zeolites; conceptual similarities; artificial enzymes; enzymes electronic ... See more keywords

Engineering globins for efficient biodegradation of malachite green: two case studies of myoglobin and neuroglobin

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recommendations! Published in 2022 at "RSC Advances"

DOI: 10.1039/d2ra02795j

Abstract: Malachite green (MG)-contaminated wastewater resulting from industrialization causes a global problem because of its toxicity and widespread usage. Compared with traditional physical and chemical approaches, biodegradation provides a new route for the degradation of MG.… read more here.

Keywords: artificial enzymes; myoglobin neuroglobin; a15c h64d; malachite green ... See more keywords