Artificial escape from XCI by DNA methylation editing of the CDKL5 gene
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DOI: 10.1093/nar/gkz1214
Abstract: Abstract A significant number of X-linked genes escape from X chromosome inactivation and are associated with a distinct epigenetic signature. One epigenetic modification that strongly correlates with X-escape is reduced DNA methylation in promoter regions.… read more here.
Keywords: dna methylation; artificial escape; cdkl5 gene; escape ... See more keywords