An Aβ42 double mutant inhibits Aβ42-induced plasma and mitochondrial membrane disruption in artificial membranes, isolated organs and intact cells.
Sign Up to like & getrecommendations! Published in 2020 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.9b00638
Abstract: Destabilization of plasma and inner mitochondrial membranes by extra- and intracellular amyloid β peptide (Aβ42) aggregates may lead to dysregulated calcium flux through the plasma membrane, mitochondrial-mediated apoptosis and neuronal cell death in patients with… read more here.
Keywords: membranes isolated; artificial membranes; plasma mitochondrial; mitochondrial membrane ... See more keywords
Bile Acids as Inducers of Protonophore and Ionophore Permeability of Biological and Artificial Membranes
Sign Up to like & getrecommendations! Published in 2023 at "Membranes"
DOI: 10.3390/membranes13050472
Abstract: It is now generally accepted that the role of bile acids in the organism is not limited to their participation in the process of food digestion. Indeed, bile acids are signaling molecules and being amphiphilic… read more here.
Keywords: membranes bile; protonophore ionophore; biological artificial; bile acids ... See more keywords