LAUSR

Artificial Organelles with Orthogonal‐Responsive Membranes for Protocell Systems: Probing the Intrinsic and Sequential Docking and Diffusion of Cargo into Two Coexisting Avidin–Polymersomes

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0 Published in 2021 at "Advanced Science"

DOI: 10.1002/advs.202004263

Abstract: Abstract The challenge of effective integration and use of artificial organelles with orthogonal‐responsive membranes and their communication in eukaryotic protocells is to understand the intrinsic membrane characteristics. Here, a novel photo‐crosslinked and pH‐responsive polymersome (Psome… read more here.

Keywords: orthogonal responsive; artificial organelles; responsive membranes; organelles orthogonal ... See more keywords

Microliter Scale Synthesis of Luciferase‐Encapsulated Polymersomes as Artificial Organelles for Optogenetic Modulation of Cardiomyocyte Beating

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1 Published in 2022 at "Advanced Science"

DOI: 10.1002/advs.202200239

Abstract: Constructing artificial systems that effectively replace or supplement natural biological machinery within cells is one of the fundamental challenges underpinning bioengineering. At the sub‐cellular scale, artificial organelles (AOs) have significant potential as long‐acting biomedical implants,… read more here.

Keywords: microliter scale; modulation; artificial organelles; synthesis ... See more keywords

Probing Crowdedness of Artificial Organelles by Clustering Polymersomes for Spatially Controlled and pH-Triggered Enzymatic Reactions.

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1 Published in 2022 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.2c00546

Abstract: Most sophisticated biological functions and features of cells are based on self-organization, and the coordination and connection between their cell organelles determines their key functions. Therefore, spatially ordered and controllable self-assembly of polymersomes to construct… read more here.

Keywords: polymersomes spatially; crowdedness artificial; probing crowdedness; artificial organelles ... See more keywords

Stimuli-responsive vesicles as distributed artificial organelles for bacterial activation

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1 Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2206563119

Abstract: Significance Artificial cells are entities designed to mimic biological cells in form and function. One of the grand challenges of this field is engineering “nonliving” artificial cells to communicate with their biological “living” counterparts. Combining… read more here.

Keywords: stimuli responsive; responsive vesicles; artificial cells; artificial organelles ... See more keywords