Albumin‐derived perfluorocarbon‐based artificial oxygen carriers: A physico‐chemical characterization and first in vivo evaluation of biocompatibility
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2017.02.015
Abstract: &NA; Until today, artificial oxygen carriers have not been reached satisfactory quality for routine clinical treatments. To bridge this gap, we designed albumin‐derived perfluorocarbon‐based nanoparticles as novel artificial oxygen carriers and evaluated their physico‐chemical and… read more here.
Keywords: oxygen; artificial oxygen; derived perfluorocarbon; albumin derived ... See more keywords
Quality by design approach identifies critical parameters driving oxygen delivery performance in vitro for perfluorocarbon based artificial oxygen carriers.
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DOI: 10.1038/s41598-021-84076-1
Abstract: Perfluorocarbons (PFCs) exhibiting high solubility for oxygen are attractive materials as artificial oxygen carriers (AOC), an alternative to whole blood or Haemoglobin-based oxygen carriers (HBOCs). PFC-based AOCs, however, met clinical translation roadblocks due to product… read more here.
Keywords: artificial oxygen; oxygen; quality design; oxygen carriers ... See more keywords
Artificial Oxygen Carriers and Red Blood Cell Substitutes: An Historic Overview and Recent Developments Toward Military and Clinical Relevance.
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DOI: 10.1097/ta.0000000000002250
Abstract: Packed red blood cells are a critical component in the resuscitation of hemorrhagic shock. The availability of donor-derived blood products, however, suffers from issues of supply, immunogenicity, and pathogenic contamination. Deployment in remote or austere… read more here.
Keywords: oxygen carriers; blood; artificial oxygen; cell ... See more keywords
Artificial Oxygen Carrier as Therapeutics Rather Than Blood Substitute for Transfusion.
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DOI: 10.1111/aor.12970
Abstract: In Kawaguchi (1), changes have been made to the following: Reference 8 has been inserted in the reference list which resulted in the renumbering of the reference list and its corresponding citations throughout the article.… read more here.
Keywords: oxygen carrier; artificial oxygen; therapeutics rather; rather blood ... See more keywords