Chemoselectivity issues of the asymmetric interaction between cyclohexanone, β-nitrostyrene, and benzoic acid under 5-aryl prolinate's organocatalysis.
Sign Up to like & getrecommendations! Published in 2020 at "Chirality"
DOI: 10.1002/chir.23212
Abstract: 4-l-menthyloxycarbonyl 5-aryl prolinates were studied as organocatalysts of a novel three-component reaction of cyclohexanone, benzoic acid, and β-nitrostyrene. The presence of ortho-halogen atom in 5-aryl fragment of the catalyst is favored for driving the formation… read more here.
Keywords: prolinate; cyclohexanone; benzoic acid; aryl prolinate ... See more keywords
Mild and Efficient Synthesis of Diverse Organo‐AuI‐L Complexes in Green Solvents
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DOI: 10.1002/cssc.201903415
Abstract: Abstract An exceptionally mild and efficient method was developed for the preparation of (hetero)aryl‐AuI‐L complexes using ethanol or water as the reaction medium at room temperature and Ar‐B(triol)K boronates as the transmetalation partner. The reaction… read more here.
Keywords: efficient synthesis; reaction; aryl; mild efficient ... See more keywords
SYNTHESIS, STRUCTURE, AND ANTIVIRAL PROPERTIES OF NOVEL 2-ADAMANTYL-5-ARYL-2 H -TETRAZOLES
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DOI: 10.1007/6073
Abstract: The reaction of 5-aryl- NH -tetrazoles with adamantan-1-ol in concentrated sulfuric acid proceeds regioselectively with the formation of the corresponding 2-adamantyl-5-aryl-2 H -tetrazoles. Nitration of these compounds leads to 2-(adamantan-1-yl)-5-(3-nitroaryl)-2 H -tetrazoles. The structures and… read more here.
Keywords: novel adamantyl; adamantyl aryl; spectroscopy; synthesis structure ... See more keywords
Synthesis of 1-aryl-6-nitro-1H-benzotriazoles by intramolecular cyclization of 1-aryl-3-(2-fluoro-4-nitrophenyl)- and 1-aryl-3-(2,4-dinitrophenyl)triazenes
Sign Up to like & getrecommendations! Published in 2018 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-018-2356-1
Abstract: Intramolecular heterocyclization of 1-aryl-3-(2-fluoro-4-nitrophenyl)- and 1-aryl-3-(2,4-dinitrophenyl)triazenes gave 1-aryl-6-nitro-1Н-benzotriazoles containing a nitro group in the benzenoid ring. read more here.
Keywords: aryl fluoro; dinitrophenyl triazenes; nitrophenyl aryl; fluoro nitrophenyl ... See more keywords
Synthesis and biological evaluation of new 2-aryl-4-((4-aryl-1H-1,2,3-triazol-1-yl)methyl)thiazole derivatives
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DOI: 10.1007/s11164-017-3164-4
Abstract: A series of 2-aryl-4-((4-aryl-1H-1,2,3-triazol-1-yl)methyl)thiazole derivatives (8a–p) have been synthesized. The structure of the newly synthesized compounds was determined by spectral analysis. The title compounds were screened for their preliminary antitubercular activity against Mycobacterium tuberculosis H37Ra… read more here.
Keywords: aryl aryl; aryl triazol; methyl thiazole; triazol methyl ... See more keywords
Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents.
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DOI: 10.1016/j.bioorg.2021.104919
Abstract: Many clinically used agents active in cancer chemotherapy exert their activity through the induction of cell death (apoptosis) by targeting microtubules, altering protein function or inhibiting DNA synthesis. The benzo[b]thiophene scaffold holds a pivotal place… read more here.
Keywords: apoptosis; thiophene; methoxybenzo; aryl ... See more keywords
Biology-oriented drug synthesis (BIODS): In vitro β-glucuronidase inhibitory and in silico studies on 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl aryl carboxylate derivatives.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2016.11.031
Abstract: Current study is based on the biology-oriented drug synthesis (BIODS) of 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl aryl carboxylate derivatives 1-26, by treating metronidazole with different aryl and hetero-aryl carboxylic acids in the presence of 1,1'-carbonyl diimidazole (CDI) as a… read more here.
Keywords: biology oriented; drug synthesis; synthesis biods; biology ... See more keywords
Installation of an aryl boronic acid function into the external section of N-aryl-oxazolidinones: Synthesis and antimicrobial evaluation.
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DOI: 10.1016/j.ejmech.2020.113002
Abstract: N-aryl-oxazolidinones is a prominent family of antimicrobials used for treating infections caused by clinically prevalent Gram-positive bacteria. Recently, boron-containing compounds have displayed intriguing potential in the antibiotic discovery setting. Herein, we report the unprecedented introduction… read more here.
Keywords: installation aryl; aryl; aryl oxazolidinones; aryl boronic ... See more keywords
Phosphorescent monometallic and bimetallic two-coordinate Au(I) complexes with N-heterocyclic carbene and aryl ligands
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DOI: 10.1016/j.ica.2020.120188
Abstract: Abstract A series of mononuclear and binuclear two coordinate Au(I) complexes consisting of a MAC carbene ligand (1,3-bis(2,6-diisopropylphenyl)-5,5-dimethyl-4-keto-tetrahydropyridylidene) and an aryl ligand, including phenyl, biphenyl, naphthyl and anthryl, are reported. The oxidation potential is controlled… read more here.
Keywords: ligand; coordinate complexes; two coordinate; carbene ... See more keywords
Cytotoxicity and DNA interaction in a series of aryl terminated iminopyridine Pt(II) complexes.
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DOI: 10.1016/j.jinorgbio.2020.111335
Abstract: A series of iminopyridine complexes of platinum(II), bearing a flexible diethereal, aryl terminated residue, where the size of aryl group is varied from phenyl to 9-anthracenyl, was synthesized. The new complexes are soluble and stable… read more here.
Keywords: aryl terminated; iminopyridine complexes; series; interaction ... See more keywords
One-pot two-step stannylation/Stille homocoupling of aryl bromides and iodides under solvent-free conditions
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DOI: 10.1016/j.mencom.2018.05.032
Abstract: A new highly efficient solvent-free method for aryl bromide (iodide) homocoupling comprising the use of Pd(OAc)2/PCy3 system in the presence of CsF is suitable for substrates bearing functional groups not tolerant to lithium-, magnesium-, zincorganic… read more here.
Keywords: pot two; step stannylation; two step; one pot ... See more keywords