Diastereoselective hydroalkylation of aryl alkenes enabled by Remote hydride transfer
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron"
DOI: 10.1016/j.tet.2020.131272
Abstract: Abstract Leveraging of 1,5-hydride shift enabled diastereoselective hydroalkylation of aryl alkenes, allowing for construction of consecutive vicinal stereogenic centers in a single process. The transformation is triggered by electrophilic alkylation of aryl alkenes with in-situ… read more here.
Keywords: hydride; diastereoselective hydroalkylation; aryl alkenes; aryl ... See more keywords
Kinetics of One-Pot Regioselective Cohydrogenation of Styrene Oxide and Aryl Alkenes: A Step toward Sustainable Development of a Novel Integrated Process for 2-Phenylethanol Production
Sign Up to like & getrecommendations! Published in 2021 at "Industrial & Engineering Chemistry Research"
DOI: 10.1021/acs.iecr.1c00154
Abstract: A strategy of one-pot regioselective cohydrogenation of styrene oxide (STOX) and aryl alkenes (styrene and alpha-methylstyrene) in the presence of aralkyl alcohols (1-phenylethanol and 2-phenyl-2-p... read more here.
Keywords: cohydrogenation styrene; styrene oxide; regioselective cohydrogenation; one pot ... See more keywords
Polyoxometalate-Incorporated Metal-Organic Network as a Heterogeneous Catalyst for Selective Oxidation of Aryl Alkenes.
Sign Up to like & getrecommendations! Published in 2022 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.2c00036
Abstract: Selective oxidation of aryl alkenes is important for chemical synthesis reactions, in which the key lies in the rational design of efficient catalysts. Herein, four polyoxometalate (POM)-incorporated metal-organic networks, with the formulas of [Co(ttb)(H2O)3]2[SiMo12O40]·2H2O (1),… read more here.
Keywords: oxidation; selective oxidation; aryl alkenes; incorporated metal ... See more keywords
1,2-Silylpyridylation Reaction of Aryl Alkenes with Silylboronate.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02074
Abstract: A metal-free silyl-pyridylation of alkenes using silyl boronates and B2pin2 through a pyridine-mediated B-interelement activation has been demonstrated, which provides a practical strategy for a variety of C4-silylalkylated pyridines. DFT calculations and control experiments show… read more here.
Keywords: reaction; reaction aryl; alkenes silylboronate; silylpyridylation reaction ... See more keywords
Exogenous Ligand-Free NiH-Catalyzed Hydroacylation of Aryl Alkenes with Aroyl Fluorides.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02110
Abstract: Acyl fluorides have emerged as efficient acyl group donors, but these attractive reagents have rarely been utilized in transition-metal-catalyzed hydroacylation. Herein we report a nickel hydride-catalyzed hydroacylation of aryl alkenes using aroyl fluorides. The reaction… read more here.
Keywords: hydroacylation; aroyl fluorides; hydroacylation aryl; catalyzed hydroacylation ... See more keywords
Synthesis of Chiral β,β-Disubstituted Ketones via CuH-Catalyzed Coupling of Aryl Alkenes and 3-Aryl-2H-azirines.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03311
Abstract: A CuH-catalyzed coupling of aryl alkenes with 3-aryl-2H-azirines has been developed to synthesize optically active β,β-disubstituted ketones. We propose that this protocol occurs through a sequence in which a chiral alkylcopper complex regioselectively attacks the… read more here.
Keywords: disubstituted ketones; coupling aryl; cuh catalyzed; aryl alkenes ... See more keywords
Selective electrocatalytic hydroboration of aryl alkenes
Sign Up to like & getrecommendations! Published in 2021 at "Green Chemistry"
DOI: 10.1039/d0gc03890c
Abstract: Organoboron compounds are powerful precursors of value-added organic compounds in synthetic chemistry, and transition metal-catalysed borylation has always been dominant. To avoid toxic reagents and costs associated with metal catalysts, simpler, more economical and effective… read more here.
Keywords: hydroboration aryl; selective electrocatalytic; electrocatalytic hydroboration; chemistry ... See more keywords
Palladium-Mediated Hydroamination of DNA-Conjugated Aryl Alkenes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2022.851674
Abstract: C-N bond formation is one of the most commonly used reactions in medicinal chemistry. Herein, we report an efficient Pd-promoted hydroamination reaction between DNA-conjugated aryl alkenes and a wide scope of aliphatic amines. The described… read more here.
Keywords: dna; dna conjugated; chemistry; hydroamination ... See more keywords