Synthesis of functionalized quinolines from the cascade reactions of N-aryl amidines with two CF3-ynones via C−H/N−H/C−N/C−C bond cleavage
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DOI: 10.1039/d3qo02070c
Abstract: Presented herein is a novel synthesis of CF3- and alkynyl-substituted quinoline derivatives based on Rh(III)-catalyzed cascade reactions of N-aryl amidines with two CF3-ynones. The formation of products involves a cascade... read more here.
Keywords: aryl amidines; reactions aryl; two cf3; cascade reactions ... See more keywords
Ru(II)-catalyzed regioselective [4 + 1] redox-neutral spirocyclization of aryl amidines with diazopyrazolones: direct access to spiro[indole-3,4'-pyrazol]-5'-ones
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DOI: 10.1039/d3qo02071a
Abstract: An efficient protocol to construct spiro[indole-3,4'-pyrazol]-5'-ones via ruthenium(II)-catalyzed selective C-H bond activation/[4 + 1] spirocyclization starting from easily available N-aryl amidines and diazopyrazolones has been developed. A series of spiro-pyrazolones... read more here.
Keywords: indole pyrazol; amidines diazopyrazolones; spiro indole; aryl amidines ... See more keywords