Selective α-bromination of aryl carbonyl compounds: prospects and challenges
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DOI: 10.1080/00397911.2019.1668415
Abstract: Abstract The α-bromination of carbonyl compounds is one of the most important transformations and also important precursors in synthetic organic chemistry. Particularly, the side chain monobromination of carbonyl compounds has been a challenging task, because… read more here.
Keywords: bromination aryl; selective bromination; carbonyl compounds; aryl carbonyl ... See more keywords
Rapid assessment of conformational preferences in biaryl and aryl carbonyl fragments
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DOI: 10.1371/journal.pone.0192974
Abstract: The ability to rapidly assess the preferred conformation of key fragments in a structure “by visual inspection” is a very useful starting point in the process of drug design. With the ability to do so,… read more here.
Keywords: conformational preference; biaryl aryl; carbonyl fragments; aryl carbonyl ... See more keywords