Palladium‐Catalyzed Chemoselective α‐Arylation of Methyl Sulfones with Aryl Chlorides
Sign Up to like & getrecommendations! Published in 2017 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.201700075
Abstract: A palladium-catalyzed α-arylation reaction of unactivated sulfones with aryl chlorides is presented. High reactivity and chemoselectivity was achieved with a combination of Buchwald's 2nd generation palladium precatalyst and Kwong's indole-based phosphine ligand. A variety of aryl… read more here.
Keywords: methyl sulfones; arylation; sulfones aryl; palladium catalyzed ... See more keywords
Visible-Light-Enhanced Suzuki-Miyaura Reactions of Aryl Chlorides in Water with Pd NPs Supported on a Conjugated Nanoporous Polycarbazole.
Sign Up to like & getrecommendations! Published in 2019 at "ChemSusChem"
DOI: 10.1002/cssc.201802918
Abstract: The visible-light-enhanced catalytic activation of aryl chlorides for Suzuki-Miyaura cross-coupling (SMC) reactions is highly challenging because of the strength of the C-Cl bond. In this work, palladium nanoparticles (Pd NPs) were grown on a conjugated… read more here.
Keywords: nanoporous polycarbazole; visible light; light enhanced; suzuki miyaura ... See more keywords
Is oxidative addition indeed the rate-determining step of the Suzuki–Miyaura reaction with less-reactive aryl chlorides under “ligand-free” conditions?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2020.121571
Abstract: Abstract The retarded oxidative addition of aryl chloride to Pd(0) is believed, by most scientists, to be the main hindrance in achieving effective conversion in the Suzuki–Miyaura reaction and other cross-coupling reactions of aryl chlorides.… read more here.
Keywords: addition; miyaura reaction; suzuki miyaura; oxidative addition ... See more keywords
Ullmann coupling of aryl chlorides in water catalyzed by palladium nanoparticles supported on amine-grafted porous aromatic polymer
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Catalysis"
DOI: 10.1016/j.mcat.2017.05.003
Abstract: Abstract A chemically stable porous carbonyl-incorporated aromatic polymer (CBAP-1(EDA)) was post-synthetically functionalized with ethylenediamine, and used as a solid support to immobilize the Pd nanoparticles (Pd@CBAP-1(EDA)) with particle size of 2–4 nm using conventional chemical reduction.… read more here.
Keywords: chlorides water; aromatic polymer; coupling aryl; spectroscopy ... See more keywords
Synthesis of N-heterocyclic carbene-Pd(II) complexes and their catalytic activity in the Buchwald-Hartwig amination of aryl chlorides
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.11.026
Abstract: Abstract Novel N-heterocyclic carbene-palladium(II) complexes using 2-picolinic acid as the ancillary ligand have been successfully developed under mild conditions. Their catalytic activity in organic synthesis has been initially tested in the Buchwald-Hartwig amination of secondary… read more here.
Keywords: hartwig amination; buchwald hartwig; catalytic activity; aryl chlorides ... See more keywords
Eumelanin as a support for efficient palladium nanoparticle catalyst for Suzuki coupling reaction of aryl chlorides in water
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2017.04.062
Abstract: Abstract Eumelanin-supported palladium (Pd) nanoparticle (NP) catalysts was found to exhibit excellent catalytic activities with high turnover number (TON, 2000) and turnover frequency (TOF, 1000 h −1 ) for Suzuki cross coupling reaction of aryl chlorides… read more here.
Keywords: water; coupling reaction; reaction; palladium nanoparticle ... See more keywords
Light-Promoted Ni-Catalyzed Cross-Coupling of Aryl Chlorides with Hydrazides: Application to the Synthesis of Rizatriptan.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c01047
Abstract: A general and highly efficient photochemical C-N coupling reaction of challenging (hetero)aryl chlorides with hydrazides is reported. Catalyzed by a Ni(II)-bipyridine complex, this reaction provides an efficient tool for the synthesis of arylhydrazines in the… read more here.
Keywords: chlorides hydrazides; synthesis rizatriptan; light promoted; synthesis ... See more keywords
Copper-Catalyzed Coupling Reaction of (Hetero)Aryl Chlorides and Amides.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b02326
Abstract: Cu2O/N,N'-bis(thiophen-2-ylmethyl)oxalamide is established to be an effective catalyst system for Goldberg amidation with inferior reactive (hetero)aryl chlorides, which have not been efficiently documented by Cu-catalysis to date. The reaction is well liberalized toward a variety… read more here.
Keywords: hetero aryl; reaction; aryl chlorides; copper catalyzed ... See more keywords
Additive-Free Palladium-Catalyzed Decarboxylative Cross-Coupling of Aryl Chlorides.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b01620
Abstract: The cross-coupling of sodium (hetero)aryl carboxylates with (hetero)aryl chlorides proceeds with 1 mol % palladium catalyst and does not require inorganic base, silver salts, or copper salts. This coupling uses two low energy partners, and… read more here.
Keywords: additive free; free palladium; aryl chlorides; cross coupling ... See more keywords
Efficient Synthesis of Aryl Boronates via Cobalt-Catalyzed Borylation of Aryl Chlorides and Bromides
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DOI: 10.1021/acscatal.8b00536
Abstract: An efficient catalytic system based on a Co(II)-NHC precursor has been developed for the cross coupling of bis(pinacolato)diboron with aryl halides including aryl chlorides, affording the aryl boronates in good to excellent yields. A wide… read more here.
Keywords: cobalt; efficient synthesis; aryl boronates; aryl ... See more keywords
Nickel-Catalyzed C–N Cross-Coupling of Ammonia, (Hetero)anilines, and Indoles with Activated (Hetero)aryl Chlorides Enabled by Ligand Design
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DOI: 10.1021/acscatal.9b03715
Abstract: The Ni(II) precatalyst (C1) featuring the phosphonite ancillary ligand Phen-DalPhos (L1) was employed in the cross-coupling of (hetero)anilines with (hetero)aryl chlorides and in the diarylation of... read more here.
Keywords: hetero anilines; hetero aryl; hetero; ligand ... See more keywords