Studies on quinazolines 7*. Alkylation of 2-aryl-4,4-diphenyl-3,4-dihydroquinazolines with methyl iodide
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DOI: 10.1007/s10593-018-2363-2
Abstract: The reaction of 2-aryl-4,4-diphenyl-3,4-dihydroquinazoline with methyl iodide in acetone in the presence of potassium hydroxide at 40°C leads to the formation of the corresponding 1-methyl-4,4-diphenyl-1,4-dihydroquinazolines and 1,3-dimethyl-4,4-diphenyl-1,4-dihydroquinazolin-3-ium iodides. The structure of 2-(7-methoxy-1,3-benzodioxol-5-yl)-1-methyl-4,4-diphenyl-1,4-dihydroquinazoline was established by… read more here.
Keywords: quinazolines alkylation; aryl diphenyl; methyl iodide; alkylation aryl ... See more keywords