Palladium-Catalyzed Cascade Approach to 12-(Aryl)indolo[1,2-c]quinazolin-6(5H)-ones
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DOI: 10.1055/s-0036-1589158
Abstract: A straightforward one-pot approach to the synthesis of challenging 12-arylindolo[1,2-c]quinazolin-6(5H)-ones is described. Starting from readily available o-(o-aminophenylethynyl)trifluoroacetanilides, palladium-catalyzed aminoarylation of the triple bond with ArI, ArBr, and ArN2 +BF4 – is followed by cyclization of… read more here.
Keywords: cascade approach; palladium catalyzed; approach; catalyzed cascade ... See more keywords