Methyl-2,2-difluoro-2-(fluorosulfonyl) acetate (MDFA)/copper (I) iodide mediated and tetrabutylammonium iodide promoted trifluoromethylation of 1-aryl-4-iodo-1,2,3-triazoles
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DOI: 10.1016/j.jfluchem.2020.109516
Abstract: Abstract While several methods are available for the synthesis of a host of trifluoromethylated heterocycles, very few of them have been applied to access 4-trifluoromethylated 1,2,3-triazoles. We report herein a general methodology for the trifluoromethylation… read more here.
Keywords: aryl iodo; tetrabutylammonium iodide; difluoro fluorosulfonyl; trifluoromethylation aryl ... See more keywords