Synthesis and properties of 5-aryl-3-diazo-3H-pyrazoles and 3-aryl-1H-pyrazole-5-diazonium salts. Preparation and cytolytic activity studies of 2-arylpyrazolo-[5,1-c][1,2,4]benzotriazines
Sign Up to like & getrecommendations! Published in 2018 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-019-02406-8
Abstract: A comparative analysis of physicochemical properties and reactivity of 3-aryl-1H-pyrazole-5-diazonium tetrafluoroborates and 5-aryl-3-diazo-3H-pyrazoles in azo coupling reactions is presented. It is shown that diazonium salts have higher reactivity compared to the respective 3-diazopyrazoles, which is… read more here.
Keywords: pyrazole diazonium; diazo pyrazoles; aryl pyrazole; diazonium ... See more keywords
Stereoisomers of an Aryl Pyrazole Glucocorticoid Receptor Agonist Scaffold Elicit Differing Anti-inflammatory Responses.
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DOI: 10.1021/acsmedchemlett.2c00299
Abstract: Glucocorticoids (GCs) are heavily prescribed to control inflammation in various human diseases; however, side effects associated with GCs are well documented and lead to serious metabolic and immunological complications with long-term use. The paradigm for… read more here.
Keywords: glucocorticoid receptor; pyrazole glucocorticoid; stereoisomers aryl; aryl pyrazole ... See more keywords