Aryl Quinazolinone Derivatives as Novel Therapeutic Agents against Brain-Eating Amoebae.
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DOI: 10.1021/acschemneuro.9b00596
Abstract: Naegleria fowleri and Balamuthia mandrillaris are protist pathogens that infect the central nervous system, causing primary amoebic meningoencephalitis and granulomatous amoebic encephalitis with mortality rates of over 95%. Quinazolinones and their derivatives possess a wide… read more here.
Keywords: quinazolinone derivatives; eating amoebae; derivatives novel; aryl quinazolinone ... See more keywords