An Investigation into the In Vitro Metabolic Stability of Aryl Sulfonyl Fluorides for their Application in Medicinal Chemistry and Radiochemistry.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00806
Abstract: Molecules that feature a sulfonyl fluoride (SO2F) moiety have been gaining increasing interest due to their unique reactivity and potential applications in synthetic chemistry, medicinal chemistry, and other biological uses. A particular interest is towards… read more here.
Keywords: radiochemistry; stability; chemistry; aryl sulfonyl ... See more keywords
An Automated Continuous Synthesis and Isolation for the Scalable Production of Aryl Sulfonyl Chlorides
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28104213
Abstract: In this work, a continuous system to produce multi-hundred-gram quantities of aryl sulfonyl chlorides is described. The scheme employs multiple continuous stirred-tank reactors (CSTRs) and a continuous filtration system and incorporates an automated process control… read more here.
Keywords: sulfonyl chlorides; aryl sulfonyl; isolation; automated continuous ... See more keywords