Palladium‐Catalyzed Chemoselective α‐Arylation of Methyl Sulfones with Aryl Chlorides
Sign Up to like & getrecommendations! Published in 2017 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.201700075
Abstract: A palladium-catalyzed α-arylation reaction of unactivated sulfones with aryl chlorides is presented. High reactivity and chemoselectivity was achieved with a combination of Buchwald's 2nd generation palladium precatalyst and Kwong's indole-based phosphine ligand. A variety of aryl… read more here.
Keywords: methyl sulfones; arylation; sulfones aryl; palladium catalyzed ... See more keywords
Ru(II)‐Catalyzed Ortho C−H Arylation of Heterocyclic Biaryls
Sign Up to like & getrecommendations! Published in 2024 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.202400463
Abstract: Ru(II)‐Pheox complexes are known catalysts for carbene insertion reactions. Herein we teach them a new trick: how to perform ortho C−H arylation processes! Our operationally simple protocol tolerates structurally diverse directing groups and both aryl… read more here.
Keywords: chemistry; arylation heterocyclic; ortho arylation; catalyzed ortho ... See more keywords
AZOLE FUNCTIONALIZATION: ADVANCES WITH DIARYLIODONIUM SALTS
Sign Up to like & getrecommendations! Published in 2025 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.202500202
Abstract: The widespread utilization of diaryliodonium salts offers promising and effective approaches towards C‐H functionalization or heteroatom‐arylation of heterocycles, presenting an alternative to traditional arylation methods. The application of diaryliodonium salts under mild conditions is particularly… read more here.
Keywords: functionalization advances; azole functionalization; arylation; diaryliodonium ... See more keywords
PdII‐Catalyzed γ‐C(sp3)–H (Hetero)arylation of Ketones Using Acetohydrazide as the Transient Directing Group
Sign Up to like & getrecommendations! Published in 2025 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.202500289
Abstract: Pd(II)‐catalyzed γ‐C(sp3)–H (hetero)arylation of aliphatic ketones is developed using acetohydrazide as the transient directing group (TDG). The reaction is facilitated by a crucial 2‐pyridone ligand via the 5,6‐membered fused palladacycle intermediate, enabling the smooth γ‐C(sp3)–H… read more here.
Keywords: catalyzed sp3; sp3 hetero; arylation; hetero arylation ... See more keywords
α ‐C−H Arylation of N ‐Sulfonyl Amines by Dual Palladium Catalysis
Sign Up to like & getrecommendations! Published in 2023 at "ChemCatChem"
DOI: 10.1002/cctc.202300392
Abstract: Functionalization of C(sp3)−H bonds adjacent to a nitrogen atom is an efficient means of preparing structurally complex amines and has long been of interest to synthetic chemists. Herein, dual palladium catalysis is used to achieve… read more here.
Keywords: arylation; dual palladium; palladium; palladium catalysis ... See more keywords
Transition Metal and Photocatalyst Free Arylation via Photoexcitable Electron Donor Acceptor Complexes:Mediation and Catalysis
Sign Up to like & getrecommendations! Published in 2024 at "ChemCatChem"
DOI: 10.1002/cctc.202301526
Abstract: Visible‐light‐activated organic reactions unlock novel avenues for complex molecular transformations, impossible under standard “thermal” conditions, which makes them powerful tools in the arsenal of synthetic chemistry. However, transition metal‐based or organic photoredox catalysts are often… read more here.
Keywords: chemistry; transition metal; eda; electron donor ... See more keywords
Empirical and Computational Insights into N-Arylation Reactions Catalyzed by Palladium meta-Terarylphosphine Catalyst.
Sign Up to like & getrecommendations! Published in 2017 at "ChemPlusChem"
DOI: 10.1002/cplu.201700042
Abstract: An in situ generated Pd-Cy*Phine catalyst has been successfully applied to the N-arylation of primary and secondary amines, and it exhibited high performance across multiple substrate classes. The performance induced by the meta-terarylphosphine motif of… read more here.
Keywords: terarylphosphine; empirical computational; arylation; computational insights ... See more keywords
Exploring Partners for the Domino α‐Arylation/Michael Addition Reaction Leading to Tetrahydroisoquinolines
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201601300
Abstract: Sulfonates, sulfonamides and phosphonates are useful nucleophiles for palladium-catalyzed intramolecular alfa-arylation leading to tetrahydroisoquinolines. While the sulfonate alfa-arylation can be successfully combined in a domino process with a broad range of Michael acceptors, only vinyl… read more here.
Keywords: michael; partners domino; domino arylation; exploring partners ... See more keywords
Solvent and Base in One: Tetra‐n‐butylammonium Acetate as a Multi‐Purpose Ionic Liquid Medium for Ru‐Catalyzed Directed Mono‐ and Di‐o‐C–H Arylation Reactions
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201701022
Abstract: Ru-catalyzed directed o-C–H arylation reactions of 2-phenylpyridine, N-phenylpyrazole, acetophenone N-(p-methoxyphenyl)imine, and 2-phenyloxazoline proceed in good to excellent yields with a number of functionalized aryl and heteroaryl bromides in neat Bu4NOAc at 120 °C. The acetate… read more here.
Keywords: ionic liquid; purpose ionic; catalyzed directed; arylation ... See more keywords
Visible-Light-Promoted Arylation Reactions Photocatalyzed by Bismuth(III) Oxide
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201701242
Abstract: Bismuth(III) oxide has been successfully applied as a photocatalyst in the arylation of heteroarenes with diazonium salts. With a low catalyst loading (1 to 5 mol%), this cheap and non-toxic semiconductor could efficiently promote the… read more here.
Keywords: iii oxide; visible light; arylation; light promoted ... See more keywords
Synthesis of Phenyl Dithiocarbamates Starting from Sodium Dialkyldithiocarbamates and Aryl Boronic Acids: a Copper Catalyzed S -Arylation
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201801271
Abstract: A convenient and efficient protocol for the S-arylation of sodium dialkyldithiocarbamates was developed. With the catalysis of copper(I) bromide, sodium dialkyldithiocarbamates coupled with aryl boronic acids giving the C-S coupling products smoothly in good to… read more here.
Keywords: boronic acids; copper; sodium; arylation ... See more keywords