Copper-Catalyzed Base-Free N-Arylation of 8-Aminoquinoline Amides through Chelation Assistance
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DOI: 10.1055/s-0037-1610906
Abstract: A new and efficient approach for the N-arylation of 8-aminoquinoline amides with diaryliodonium salts has been developed. This chelation-assisted selective C–N cross-coupling reaction gave the desired N-arylated 8-aminoquinoline in moderate to good yields. In contrast… read more here.
Keywords: chelation; aminoquinoline amides; arylation aminoquinoline; aminoquinoline ... See more keywords