Articles with "arylation indoles" as a keyword



External Base‐Free Approach for Copper‐Catalyzed N‐Arylation of Indoles and Pyrroles in Green Reaction Medium

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Published in 2025 at "Applied Organometallic Chemistry"

DOI: 10.1002/aoc.7966

Abstract: N‐Arylated heterocyclic molecules are extensively found as key components in numerous pharmaceutical and agrochemical compounds. Herein, inexpensive 1,10‐phenanthroline‐assisted copper‐catalyzed sustainable greener methodology has been developed for N‐arylation of indoles and pyrrole under commercial base and… read more here.

Keywords: reaction; chemistry; arylation indoles; base ... See more keywords

On the Barton Copper-Catalyzed C3-Arylation of Indoles using Triarylbismuth bis(trifluoroacetate) Reagents.

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Published in 2023 at "ChemPlusChem"

DOI: 10.1002/cplu.202300218

Abstract: Invited for this month's cover are the collaborating groups of Prof. Alexandre Gagnon at the Université du Québec à Montréal in Canada, and Dr. Claire McMullin at the University of Bath in the UK. The… read more here.

Keywords: copper; indoles using; arylation indoles; catalyzed arylation ... See more keywords

Palladium-Catalyzed 2-fold C-H Activation/C-C Coupling for C4-Arylation of Indoles Using Weak Chelation.

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Published in 2021 at "Organic letters"

DOI: 10.1021/acs.orglett.1c03970

Abstract: Palladium-catalyzed weak chelation-assisted regioselective C4-arylation of indoles has been accomplished using a readily available arene at moderate temperature. The C4-arylation, weak chelating benzoyl (Bz) directing group, cross-dehydrogenative coupling (CDC), broad substrate scope, and late-stage diversifications… read more here.

Keywords: arylation; arylation indoles; catalyzed fold; palladium catalyzed ... See more keywords

C3-Arylation of indoles with aryl ketones via C-C/C-H activations.

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Published in 2021 at "Chemical communications"

DOI: 10.1039/d1cc03954g

Abstract: C3-Arylation of indoles with aryl ketones is accomplished via palladium-catalyzed ligand-promoted Ar-C(O) cleavage and subsequent C-H arylation of indole. Various (hetero)aryl ketones are compatible in this reaction, affording the corresponding 3-arylindoles in moderate to good… read more here.

Keywords: ketones via; aryl ketones; arylation indoles; via activations ... See more keywords