Development of 2-arylbenzo[h]quinolone analogs as selective CYP1B1 inhibitors
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DOI: 10.1039/c8ra00465j
Abstract: The CYP1B1 enzyme is regarded as a potential target for cancer prevention and therapy. Based on the structure of α-naphthoflavone (ANF), diverse 2-arylbenzo[h]quinolone derivatives were designed, synthesized and evaluated as selective CYP1B1 inhibitors. Compared with… read more here.
Keywords: cyp1b1; cyp1b1 inhibitors; selective cyp1b1; arylbenzo quinolone ... See more keywords