Catalytic enantioselective hydrophosphinylation of in situ-generated indole-derived vinylogous imines to access 3-(1-diphenylphosphoryl-arylmethyl)indoles.
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DOI: 10.1039/d2cc04763b
Abstract: An efficient organocatalyzed enantioselective hydrophosphinylation of indole-derived vinylogous imines generated in situ from sulfonyl indoles has been developed. Using quinine-derived bifunctional thiourea as the catalyst, a wide range of structurally diverse chiral 3-(1-diphenylphosphoryl-arylmethyl)indoles were obtained… read more here.
Keywords: diphenylphosphoryl arylmethyl; derived vinylogous; vinylogous imines; enantioselective hydrophosphinylation ... See more keywords