Arylsulfanyl groups - Suitable side chains for 5-substituted 1,10-phenanthroline and nickel complexes as G4 ligands and telomerase inhibitors.
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DOI: 10.1016/j.jinorgbio.2017.04.018
Abstract: Guanine-rich DNA sequences can undergo self-assembly into unique G-quadruplex structures that interfere with the binding of proteins to the same DNA region. The formation of DNA G-quadruplexes requires monovalent cations (Na+ and K+) or small… read more here.
Keywords: side chains; arylsulfanyl groups; dna; quadruplex dna ... See more keywords