Unexpected decarboxamidation of α-arylsulfonyl Weinreb amides by Grignard reagents: Synthesis of α-disubstituted arylsulfones
Sign Up to like & getrecommendations! Published in 2017 at "Chemical Research in Chinese Universities"
DOI: 10.1007/s40242-017-6371-z
Abstract: An unexpected decarboxamidation of α-arylsulfonyl Weinreb amides as a side reaction under the standard acylating conditions was found in Weinreb amides chemistry. The control experiments for mechanism study disclosed that α-sulfo group was necessary, and… read more here.
Keywords: unexpected decarboxamidation; weinreb amides; arylsulfonyl weinreb; decarboxamidation arylsulfonyl ... See more keywords