Synthesis and biological evaluation of novel 2-arylvinyl-substituted naphtho[2,3-d]imidazolium halide derivatives as potent antitumor agents.
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DOI: 10.1016/j.ejmech.2017.12.008
Abstract: Two series of novel 2-arylvinyl-naphtho[2,3-d]imidazol-3-ium iodide derivatives and 2-arylvinyl-naphtho[2,3-d]imidazol-3-ium bromide derivatives were designed and synthesized by the structural combination of YM155 with stilbenoids. All compounds were tested for anti-proliferative activity against PC-3, A375 and HeLa… read more here.
Keywords: novel arylvinyl; arylvinyl substituted; naphtho imidazolium; substituted naphtho ... See more keywords