α‐Asarone attenuates chronic sciatica by inhibiting peripheral sensitization and promoting neural repair
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7603
Abstract: This study explored the therapeutic effect of α‐asarone on chronic sciatica. Thirty‐two Sprague–Dawley (SD) rats were divided into four groups: the sham group, chronic constriction injury (CCI) group, pregabalin group, and α‐asarone group. Hot hyperalgesia… read more here.
Keywords: chronic sciatica; inhibiting peripheral; group; asarone ... See more keywords
Chiral resolution, absolute configuration, and bioactivity of a new racemic asarone derivative from the rhizome of Acorus tatarinowii.
Sign Up to like & getrecommendations! Published in 2017 at "Fitoterapia"
DOI: 10.1016/j.fitote.2017.08.004
Abstract: A new asarone-derived racemate (1) was isolated from the rhizome of Acorus tatarinowii. The structure of 1 was established by comprehensive spectroscopic analyses, and it was successfully resolved by chiral HPLC, demonstrating that it is… read more here.
Keywords: asarone; chiral resolution; rhizome acorus; acorus tatarinowii ... See more keywords
Asarone and metformin delays experimentally induced hepatocellular carcinoma in diabetic milieu.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.05.046
Abstract: AIMS The evidence suggests that the hyperglycemia and hyperinsulinemia of diabetes mellitus (DM) are risk factors for the development of hepatocellular carcinoma (HCC). The aim of the present study was to examine the effect of… read more here.
Keywords: hepatocellular carcinoma; hcc; stz; den ... See more keywords
Effect of α-asarone on ethanol-induced learning and memory impairment in mice and its underlying mechanism.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.116898
Abstract: AIMS Learning and memory impairment is a common symptom in the early stages of various types of dementia. It is likely to reduce the incidence of dementia with correct intervention. α-Asarone is the main bioactive… read more here.
Keywords: memory impairment; learning memory; underlying mechanism; asarone ... See more keywords
Neuroprotective Effect of Alpha-asarone on the Rats Model of Cerebral Ischemia–Reperfusion Stroke via Ameliorating Glial Activation and Autophagy
Sign Up to like & getrecommendations! Published in 2021 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2021.08.006
Abstract: Alpha-asarone, a major active component isolated from Acorus gramineus, can affect brain functions and behaviors by multiple mechanisms. However, the effect of alpha-asarone on cerebral ischemia-reperfusion (CIR) stroke has not been reported. The present study… read more here.
Keywords: neuroprotective effect; alpha asarone; reperfusion; effect alpha ... See more keywords
Borneol and Α-asarone as adjuvant agents for improving blood–brain barrier permeability of puerarin and tetramethylpyrazine by activating adenosine receptors
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DOI: 10.1080/10717544.2018.1516005
Abstract: Abstract Puerarin (PUE) and tetramethylpyrazine (TMP) are central nervous system (CNS) drugs used in cerebrovascular diseases. Poor brain–blood barrier (BBB) permeability limited their clinical application. Borneol and α-asarone have been proposed as an oral brain-targeting… read more here.
Keywords: adjuvant agents; pue tmp; adenosine receptors; asarone ... See more keywords
Phase II Metabolism of Asarone Isomers In Vitro and in Humans Using HPLC-MS/MS and HPLC-qToF/MS
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DOI: 10.3390/foods10092032
Abstract: (1) Background: Metabolism data of asarone isomers, in particular phase II, in vitro and in humans is limited so far. For the first time, phase II metabolites of asarone isomers were characterized and human kinetic… read more here.
Keywords: vitro humans; phase; hplc; metabolism ... See more keywords
The Toxicity, Sublethal Effects, and Biochemical Mechanism of β-Asarone, a Potential Plant-Derived Insecticide, against Bemisia tabaci
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810462
Abstract: Bemisia tabaci is a threat to agriculture worldwide because of its potential to cause devastating damage to various crops. β-asarone is a bioactive pesticidal chemical originating from Acorus calamus (or “Sweet Flag”) plants, and it… read more here.
Keywords: toxicity; asarone; bemisia tabaci; sublethal effects ... See more keywords