Revealing the Antiepileptic Effect of α-Asaronol on Pentylenetetrazole-Induced Seizure Rats Using NMR-Based Metabolomics
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c06922
Abstract: α-Asaronol from Acorus tatarinowii (known as “Shichangpu” in Traditional Chinese medicine) has been proved to possess more efficient antiepileptic activity and lower toxicity than α-asarone (namely “Xixinnaojiaonang” as an antiepileptic drug in China) in our… read more here.
Keywords: induced seizure; seizure rats; based metabolomics; asaronol ... See more keywords
Positive Effect of α-Asaronol on the Incidence of Post-Stroke Epilepsy for Rat with Cerebral Ischemia-Reperfusion Injury
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27061984
Abstract: In the present study, we confirmed that α-asaronol, which is a product of the active metabolites of alpha Asarone, did not affect n-butylphthalide efficacy when n-butylphthalide and α-asaronol were co-administered to rats with cerebral ischemia-reperfusion… read more here.
Keywords: cerebral ischemia; reperfusion injury; ischemia reperfusion; asaronol ... See more keywords