Isoformononetin, a dietary isoflavone protects against streptozotocin induced rat model of neuroinflammation through inhibition of NLRP3/ASC/IL-1 axis activation.
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DOI: 10.1016/j.lfs.2021.119989
Abstract: AIMS Isoformononetin (IFN), a methoxyl isoflavone present in most of human dietary supplements. However, being a highly potent antioxidant and anti-inflammatory molecule, its activity against neuronal oxidative stress and neuroinflammation has not been explored till… read more here.
Keywords: nlrp3 asc; streptozotocin induced; asc; neuroinflammation ... See more keywords