LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "ascending dose" as a keyword



Photo from wikipedia

Intranasal dexmedetomidine in elderly subjects with or without beta blockade: a randomised double-blind single-ascending-dose cohort study.

Sign Up to like & get
recommendations! Published in 2020 at "British journal of anaesthesia"

DOI: 10.1016/j.bja.2019.12.025

Abstract: BACKGROUND The aim of this double-blind, placebo-controlled, single-ascending-dose study was to determine the safety and tolerability of intranasal dexmedetomidine in the elderly. METHODS We randomly assigned 48 surgical patients ≥65 yr of age to receive… read more here.

Keywords: double blind; intranasal dexmedetomidine; dexmedetomidine elderly; single ascending ... See more keywords

Phase I Single Ascending Dose and Food Effect Study in Healthy Adults and Phase I/IIa Multiple Ascending Dose Study in Patients with Pulmonary Tuberculosis to Assess Pharmacokinetics, Bactericidal Activity, Tolerability, and Safety of OPC-167832

Sign Up to like & get
recommendations! Published in 2023 at "Antimicrobial Agents and Chemotherapy"

DOI: 10.1128/aac.01477-22

Abstract: OPC-167832, an inhibitor of decaprenylphosphoryl-β-d-ribose 2’-oxidase, demonstrated potent antituberculosis activity and a favorable safety profile in preclinical studies. This report describes the first two clinical studies of OPC-167832: (i) a phase I single ascending dose… read more here.

Keywords: single ascending; opc 167832; ascending dose; activity ... See more keywords
Photo from wikipedia

Safety, tolerance, and pharmacokinetics of salvianolic acid B in healthy Chinese volunteers: A randomized, double-blind, placebo-controlled phase 1 clinical trial

Sign Up to like & get
recommendations! Published in 2023 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2023.1146309

Abstract: Background: Salvianolic acid B (Sal B) is one of the main active ingredients of Salvia miltiorrhiza Bunge. In China, many traditional Chinese medicines have been modified into injections for higher bioavailability and better efficacy. Salvianolic… read more here.

Keywords: safety; dose study; ascending dose; salvianolic acid ... See more keywords