Deformability of ascending thoracic aorta aneurysms assessed using ultrafast ultrasound and a principal strain estimator: In vitro evaluation and in vivo feasibility.
Sign Up to like & getrecommendations! Published in 2022 at "Medical physics"
DOI: 10.1002/mp.15464
Abstract: BACKGROUND Noninvasive vascular strain imaging under conventional line-by-line scanning has a low frame rate and lateral resolution, and depends on the coordinate system. It is thus affected by high deformations due to image decorrelation between… read more here.
Keywords: strain estimator; principal strain; strain; deformability ... See more keywords
Fluid- and Biomechanical Analysis of Ascending Thoracic Aorta Aneurysm with Concomitant Aortic Insufficiency
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Biomedical Engineering"
DOI: 10.1007/s10439-017-1913-6
Abstract: We present a comprehensive and original framework for the biomechanical analysis of patients affected by ascending thoracic aorta aneurysm and aortic insufficiency. Our aim is to obtain crucial indications about the role played by deranged… read more here.
Keywords: thoracic aorta; analysis; aorta aneurysm; aortic insufficiency ... See more keywords
Experimental and Mouse-Specific Computational Models of the Fbln4SMKO Mouse to Identify Potential Biomarkers for Ascending Thoracic Aortic Aneurysm
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular Engineering and Technology"
DOI: 10.1007/s13239-021-00600-4
Abstract: Purpose To use computational methods to explore geometric, mechanical, and fluidic biomarkers that could correlate with mouse lifespan in the Fbln4 SMKO mouse. Mouse lifespan was used as a surrogate for risk of a severe… read more here.
Keywords: ascending thoracic; mouse; thoracic aortic; mouse specific ... See more keywords
Prediction of local strength of ascending thoracic aortic aneurysms.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.1016/j.jmbbm.2020.104284
Abstract: Knowledges of both local stress and strength are needed for a reliable evaluation of the rupture risk for ascending thoracic aortic aneurysm (ATAA). In this study, machine learning is applied to predict the local strength… read more here.
Keywords: strength; rupture; ascending thoracic; thoracic aortic ... See more keywords
Association of 3-Year All-Cause Mortality and Peak Wall Stresses of Ascending Thoracic Aortic Aneurysms in Veterans.
Sign Up to like & getrecommendations! Published in 2022 at "Seminars in thoracic and cardiovascular surgery"
DOI: 10.1053/j.semtcvs.2022.06.002
Abstract: Risk of aortic dissection in ascending thoracic aortic aneurysms is not sufficiently captured by size-based metrics. From a biomechanical perspective, dissection may be initiated when wall stress exceeds wall strength. Our objective was to assess… read more here.
Keywords: wall stresses; thoracic aortic; cause mortality; mortality ... See more keywords
Fate of the unoperated ascending thoracic aortic aneurysm: three-decade experience from the Aortic Institute at Yale University.
Sign Up to like & getrecommendations! Published in 2023 at "European heart journal"
DOI: 10.1093/eurheartj/ehad148
Abstract: AIMS This study aims to outline the 'true' natural history of ascending thoracic aortic aneurysm (ATAA) based on a cohort of patients not undergoing surgical intervention. METHODS AND RESULTS The outcomes, risk factors, and growth… read more here.
Keywords: aortic size; growth; thoracic aortic; aortic aneurysm ... See more keywords
Relationship between ascending thoracic aortic diameter and blood pressure, a Mendelian randomization study
Sign Up to like & getrecommendations! Published in 2022 at "Arteriosclerosis, thrombosis, and vascular biology"
DOI: 10.1161/atvbaha.122.318149
Abstract: Background: Observational studies identified elevated blood pressure (BP) as a strong risk factor for thoracic aortic dilation, and BP reduction is the primary medical intervention recommended to prevent progression of aortic aneurysms. However, although BP… read more here.
Keywords: thoracic aortic; mendelian randomization; pressure; estimate ... See more keywords
Fully-Coupled FSI Computational Analyses in the Ascending Thoracic Aorta Using Patient-Specific Conditions and Anisotropic Material Properties
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.732561
Abstract: Computational hemodynamics has become increasingly important within the context of precision medicine, providing major insight in cardiovascular pathologies. However, finding appropriate compromise between speed and accuracy remains challenging in computational hemodynamics for an extensive use… read more here.
Keywords: patient specific; fully coupled; thoracic aorta; ascending thoracic ... See more keywords
In Vitro Analysis of Hemodynamics in the Ascending Thoracic Aorta: Sensitivity to the Experimental Setup
Sign Up to like & getrecommendations! Published in 2023 at "Applied Sciences"
DOI: 10.3390/app13085095
Abstract: We perform a stochastic sensitivity analysis of the experimental setup of a mock circulatory loop for in vitro hemodynamics analysis in the ascending thoracic aorta at a patient-specific level. The novelty of the work is… read more here.
Keywords: setup; sensitivity; analysis; thoracic aorta ... See more keywords
Patient-Specific Analysis of Ascending Thoracic Aortic Aneurysm with the Living Heart Human Model
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineering"
DOI: 10.3390/bioengineering8110175
Abstract: In ascending thoracic aortic aneurysms (ATAAs), aneurysm kinematics are driven by ventricular traction occurring every heartbeat, increasing the stress level of dilated aortic wall. Aortic elongation due to heart motion and aortic length are emerging… read more here.
Keywords: patient specific; aneurysm; heart; ascending thoracic ... See more keywords