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Published in 2019 at "Environmental Toxicology"
DOI: 10.1002/tox.22888
Abstract: Cancer is the major cause of death and many factors that lead to its occurrences, such as environmental pollution and pesticides and other factors. Ehrlich carcinoma development depends on many things associated with the environment,…
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Keywords:
ascites carcinoma;
group;
effects vitamin;
vitamin b17 ... See more keywords
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Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.03.012
Abstract: An expression of calpain and caspase-1 as well as the concomitant ultrastructural alterations were investigated during necrosis of the mouse Ehrlich ascites carcinoma. The calpain expression was registered at 0 h and 1 h although caspase-1 did…
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Keywords:
ascites carcinoma;
calpain;
calpain caspase;
expression ... See more keywords
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Published in 2018 at "Heliyon"
DOI: 10.1016/j.heliyon.2018.e00661
Abstract: In an effort to discover an effective and selective antitumour agent, synthesis and anti-cancer potential of 4-(pyridin-4-yl)-6-(thiophen-2-yl) pyrimidin-2(1H)-one (SK-25), which has been reported earlier by us with significant cytotoxicity towards MiaPaCa-2 malignant cells, with an…
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Keywords:
ascites carcinoma;
sarcoma 180;
pyridin thiophen;
thiophen pyrimidin ... See more keywords
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Published in 2017 at "MedChemComm"
DOI: 10.1039/c6md00618c
Abstract: Cisplatin as a chief chemotherapy has nephro-toxicity and so we have tried to develop a novel antitumor drug based on a combination of cobalt metal ion with an organic moiety. The antitumor activity of the…
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Keywords:
ascites carcinoma;
cobalt complex;
cobalt;
murine ehrlich ... See more keywords
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Published in 2017 at "Tumor Biology"
DOI: 10.1177/1010428317695933
Abstract: Peritoneal carcinomatosis is considered as a potentially lethal clinical condition, and the therapeutic options are limited. The antitumor effectiveness of the [Ru(l-Met)(bipy)(dppb)]PF6 (1) and the [Ru(l-Trp)(bipy)(dppb)]PF6 (2) complexes were evaluated in the peritoneal carcinomatosis model,…
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Keywords:
ascites carcinoma;
amino acid;
ehrlich ascites;
mechanism action ... See more keywords
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Published in 2020 at "Current Drug Therapy"
DOI: 10.2174/1574885514666191211122437
Abstract: Background: Development of effective cancer-chemotherapy is the most challenging field due to toxicity of chemo-agents. Objective: As chalcone has been known to have pharmacological applications, here we aimed to synthesized three chalcone derivatives, 2',4'-dihydroxy-3,4-methylenedioxychalcone (C1),…
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Keywords:
ascites carcinoma;
apoptosis;
eac cells;
dihydroxy methylenedioxychalcone ... See more keywords
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Published in 2018 at "Nanomedicine"
DOI: 10.2217/nnm-2017-0394
Abstract: AIM This study aimed to evaluate, for the first time the potential use of a safe biocompatible nanoformulation of silymarin (SM) as antitumor agent and to provide its mechanism of action compared with native SM.…
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Keywords:
ascites carcinoma;
agent;
nanoformulation potential;
ehrlich ascites ... See more keywords