Ascorbate deficiency increases quiescence and self-renewal in hematopoietic stem cells and multipotent progenitors
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DOI: 10.1182/blood.2024024769
Abstract: Key Points • Deletion of the ascorbate transporter, Slc23a2, increases quiescence and self-renewal potential in HSCs and multipotent progenitors.• Ascorbate deficiency is sufficient to confer long-term self-renewal potential on MPPs. read more here.
Keywords: ascorbate deficiency; self renewal; self; increases quiescence ... See more keywords