Neonatal Tbr1 Dosage Controls Cortical Layer 6 Connectivity
Sign Up to like & getrecommendations! Published in 2018 at "Neuron"
DOI: 10.1016/j.neuron.2018.09.027
Abstract: An understanding of how heterozygous loss-of-function mutations in autism spectrum disorder (ASD) risk genes, such as TBR1, contribute to ASD remains elusive. Conditional Tbr1 deletion during late mouse gestation in cortical layer 6 neurons (Tbr1layer6… read more here.
Keywords: tbr1 dosage; cortical layer; layer; neonatal tbr1 ... See more keywords
Autism Spectrum Disorders in Children Exposed in Utero to Hyperemesis Gravidarum.
Sign Up to like & getrecommendations! Published in 2019 at "American journal of perinatology"
DOI: 10.1055/s-0039-1696670
Abstract: OBJECTIVE This study aimed to determine if hyperemesis gravidarum (HG) is associated with autism spectrum disorder (ASD) risk, and how this association is influenced by race, ethnicity, sex, exposure timing, and medication used to treat… read more here.
Keywords: risk; exposed utero; hyperemesis gravidarum; children exposed ... See more keywords
Using Zebrafish to Model Autism Spectrum Disorder: A Comparison of ASD Risk Genes Between Zebrafish and Their Mammalian Counterparts
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2020.575575
Abstract: Autism spectrum disorders (ASDs) are a highly variable and complex set of neurological disorders that alter neurodevelopment and cognitive function, which usually presents with social and learning impairments accompanied with other comorbid symptoms like hypersensitivity… read more here.
Keywords: asd risk; autism spectrum; risk genes;