Sequencing of selected chromatin remodelling genes reveals increased burden of rare missense variants in ASD patients from the Japanese population
Sign Up to like & getrecommendations! Published in 2022 at "International Review of Psychiatry"
DOI: 10.1080/09540261.2022.2072193
Abstract: Abstract Chromatin remodelling is an important process in neural development and is related to autism spectrum disorder (ASD) and schizophrenia (SCZ) aetiology. To further elucidate the involvement of chromatin remodelling genes in the genetic aetiology… read more here.
Keywords: chromatin remodelling; rare missense; missense variants; chromatin ... See more keywords
Impaired Object Recognition but Normal Social Behavior and Ultrasonic Communication in Cofilin1 Mutant Mice
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2018.00025
Abstract: Autism spectrum disorder (ASD), schizophrenia (SCZ) and intellectual disability (ID) show a remarkable overlap in symptoms, including impairments in cognition, social behavior and communication. Human genetic studies revealed an enrichment of mutations in actin-related genes… read more here.
Keywords: cofilin1 mutant; communication; cofilin1; asd scz ... See more keywords