Development of 11C-Labeled ASEM Analogues for the Detection of Neuronal Nicotinic Acetylcholine Receptors (α7-nAChR)
Sign Up to like & getrecommendations! Published in 2022 at "ACS Chemical Neuroscience"
DOI: 10.1021/acschemneuro.1c00730
Abstract: The homo-pentameric alpha 7 receptor is one of the major types of neuronal nicotinic acetylcholine receptors (α7-nAChRs) related to cognition, memory formation, and attention processing. The mapping of α7-nAChRs by PET pulls a lot of… read more here.
Keywords: acetylcholine receptors; asem analogues; development; nicotinic acetylcholine ... See more keywords
In silico studies of ASEM analogues targeting α7-nAChR and experimental verification
Sign Up to like & getrecommendations! Published in 2021 at "RSC Advances"
DOI: 10.1039/d0ra10435c
Abstract: The in silico binding free energies of the ASEM analogues targeting α7-nAChR are in line with the inhibition obtained from in vitro binding assays. read more here.
Keywords: silico studies; targeting nachr; analogues targeting; asem analogues ... See more keywords