Patterns of alveolar macrophage activation upon attenuated and virulent African swine fever viruses in vitro.
Sign Up to like & getrecommendations! Published in 2020 at "Comparative immunology, microbiology and infectious diseases"
DOI: 10.1016/j.cimid.2020.101513
Abstract: The pattern of porcine alveolar macrophage (AM) activation upon classical stimuli of two strains of African swine fever (ASF) viruses, an attenuated ASFV-BA71V and virulent ASFV-Georgia2007 were investigated. In an in vitro experiment ASFV-Georgia2007-infected AM… read more here.
Keywords: asfv; asfv ba71v; alveolar macrophage; asfv georgia2007 ... See more keywords
The L83L ORF of African swine fever virus strain Georgia encodes for a non-essential gene that interacts with the host protein IL-1β.
Sign Up to like & getrecommendations! Published in 2018 at "Virus research"
DOI: 10.1016/j.virusres.2018.03.017
Abstract: African swine fever virus (ASFV) causes a contagious and frequently lethal disease of pigs causing significant economic consequences to the swine industry. The ASFV genome encodes for more than 150 genes, but only a few… read more here.
Keywords: protein; asfv; swine fever; african swine ... See more keywords
African swine fever virus vaccine candidate ASFV-G-DI177L efficiently protects European and native pig breeds against circulating Vietnamese field strain.
Sign Up to like & getrecommendations! Published in 2021 at "Transboundary and emerging diseases"
DOI: 10.1111/tbed.14329
Abstract: The recent spread of African swine fever (ASF) in the People's Republic of China and neighboring countries in Asia has had significant economic consequences with an estimated direct cost of $55 billion - $130 billion.… read more here.
Keywords: strain; asfv; vaccine candidate; swine ... See more keywords
Rethinking the uncertainty of African swine fever virus contamination in feed ingredients and risk of introduction into the United States.
Sign Up to like & getrecommendations! Published in 2021 at "Transboundary and emerging diseases"
DOI: 10.1111/tbed.14358
Abstract: Economically relevant pathogens, such as African swine fever virus (ASFV), have been shown to survive when experimentally inoculated in some feed ingredients under the environmental conditions in transoceanic transport models. However, these models did not… read more here.
Keywords: asfv; risk; feed ingredients; probability ... See more keywords
Deletion of DP148R, DP71L, and DP96R Attenuates African Swine Fever Virus, and the Mutant Strain Confers Complete Protection against Homologous Challenges in Pigs
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Virology"
DOI: 10.1128/jvi.00247-23
Abstract: Ongoing outbreaks of African swine fever (ASF) have considerably damaged the pig industry in affected countries. Thus, a safe and effective vaccine is important to control African swine fever spread. ABSTRACT The African swine fever… read more here.
Keywords: swine fever; african swine; virus; asfv ... See more keywords
Combinational Deletions of MGF360-9L and MGF505-7R Attenuated Highly Virulent African Swine Fever Virus and Conferred Protection against Homologous Challenge
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.00329-22
Abstract: Currently, the deficiency in commercially available vaccines or therapeutic options against African swine fever constitutes a matter of major concern in the swine industry globally. Here, we report the design and construction of a recombinant… read more here.
Keywords: mgf360 mgf505; swine fever; african swine; combinational deletions ... See more keywords
Deletion of the H108R Gene Reduces Virulence of the Pandemic Eurasia Strain of African Swine Fever Virus with Surviving Animals Being Protected against Virulent Challenge
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.00545-22
Abstract: Currently, there is no commercial vaccine available to prevent ASF. ASFV-Georgia2007 (ASFV-G) and its field isolate derivatives are producing a large pandemic which is drastically affecting pork production in Eurasia. ABSTRACT African swine fever virus… read more here.
Keywords: h108r; swine; virus; asfv ... See more keywords
African Swine Fever Virus and Host Response: Transcriptome Profiling of the Georgia 2007/1 Strain and Porcine Macrophages
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.01939-21
Abstract: African swine fever virus (ASFV) causes hemorrhagic fever in domestic pigs, with case fatality rates approaching 100% and no approved vaccines or antivirals. The highly virulent ASFV Georgia 2007/1 strain (GRG) was the first isolated… read more here.
Keywords: swine fever; asfv; strain; host ... See more keywords
CP204L Is a Multifunctional Protein of African Swine Fever Virus That Interacts with the VPS39 Subunit of the Homotypic Fusion and Vacuole Protein Sorting Complex and Promotes Lysosome Clustering
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Virology"
DOI: 10.1128/jvi.01943-22
Abstract: African swine fever virus (ASFV) was first identified over a hundred years ago. Since then, much effort has been made to understand the pathogenesis of ASFV. ABSTRACT Virus replication depends on a complex interplay between… read more here.
Keywords: fever virus; swine fever; african swine; virus ... See more keywords
Immunization of Pigs by DNA Prime and Recombinant Vaccinia Virus Boost To Identify and Rank African Swine Fever Virus Immunogenic and Protective Proteins
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Virology"
DOI: 10.1128/jvi.02219-17
Abstract: ABSTRACT African swine fever virus (ASFV) causes an acute hemorrhagic fever in domestic pigs, with high socioeconomic impact. No vaccine is available, limiting options for control. Although live attenuated ASFV can induce up to 100%… read more here.
Keywords: asfv; vaccinia virus; recombinant vaccinia; prime recombinant ... See more keywords
African Swine Fever Virus Armenia/07 Virulent Strain Controls Interferon Beta Production through the cGAS-STING Pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Virology"
DOI: 10.1128/jvi.02298-18
Abstract: African swine fever, a devastating disease for domestic pigs and wild boar, is currently spreading in Europe, Russia, and China, becoming a global threat with huge economic and ecological consequences. One interesting aspect of ASFV… read more here.
Keywords: infection; cgas sting; asfv; cgas ... See more keywords