Asialoglycoprotein receptor targeted delivery of doxorubicin nanoparticles for hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Drug Delivery"
DOI: 10.1080/10717544.2016.1225856
Abstract: Abstract We report asialoglycoprotein receptor (ASGPR)-targeted doxorubicin hydrochloride (Dox) nanoparticles (NPs) for hepatocellular carcinoma (HCC). Polyethylene sebacate (PES)-Gantrez® AN 119 Dox NPs of average size 220 nm with PDI read more here.
Keywords: hepatocellular carcinoma; delivery; asialoglycoprotein receptor; agn ... See more keywords
Asialoglycoprotein receptor 1 functions as a tumor suppressor in liver cancer via inhibition of STAT3.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer research"
DOI: 10.1158/0008-5472.can-21-4337
Abstract: Liver cancer is characterized by aggressive growth and high mortality. Asialoglycoprotein receptor 1 (ASGR1), which is expressed almost exclusively in liver cells, is reduced in liver cancer. However, the specific mechanism of ASGR1 function in… read more here.
Keywords: liver cancer; stat3; asialoglycoprotein receptor; tumor ... See more keywords