Pharmacokinetics and pharmacogenetics of the MEK1/2 inhibitor, selumetinib, in Asian and Western healthy subjects: a pooled analysis
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DOI: 10.1007/s00228-017-2217-3
Abstract: PurposeEmerging data on selumetinib, a MEK1/2 inhibitor in clinical development, suggest a possible difference in pharmacokinetics (PK) between Japanese and Western patients. This pooled analysis sought to assess the effect of ethnicity on selumetinib exposure… read more here.
Keywords: selumetinib; analysis; mek1 inhibitor; asian subjects ... See more keywords