The mechanosensitive ion channel ASIC2 mediates both proprioceptive sensing and spinal alignment.
Sign Up to like & getrecommendations! Published in 2023 at "Experimental physiology"
DOI: 10.1113/ep090776
Abstract: NEW FINDINGS What is the central question of this study? Proprioception is initiated by mechanosensitive neurons. However, the identities of the molecular players that mediate proprioceptive sensing are largely unknown. Here, we aimed to identify… read more here.
Keywords: ion channel; proprioceptive sensing; asic2; alignment ... See more keywords
Loss of Acid-Sensing Ion Channel 2 Enhances Pulmonary Vascular Resistance and Hypoxic Pulmonary Hypertension.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00894.2018
Abstract: Acid-sensing ion channels (ASICs) are voltage-insensitive cation channels that contribute to cellular excitability. We previously reported that ASIC1 in pulmonary artery smooth muscle cells (PASMC) contribute to pulmonary vasoreactivity and vascular remodeling during the development… read more here.
Keywords: pulmonary hypertension; pulmonary vascular; induced pulmonary; asic2 ... See more keywords