Acid-sensing ion channel 3: An analgesic target
Sign Up to like & getrecommendations! Published in 2020 at "Channels"
DOI: 10.1080/19336950.2020.1852831
Abstract: ABSTRACT Acid-sensing ion channel 3 (ASIC3) belongs to the epithelial sodium channel/degenerin (ENaC/DEG) superfamily. There are 7 different ASIC subunits encoded by 5 different genes. Most ASIC subunits form trimeric ion channels that upon activation… read more here.
Keywords: sensing ion; asic3; ion channel; channel ... See more keywords
Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3.
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DOI: 10.1158/0008-5472.can-15-3545
Abstract: Multiple myeloma patients experience severe bone pain (MMBP) that is undertreated and poorly understood. In this study, we studied MMBP in an intratibial mouse xenograft model that employs JJN3 human multiple myeloma cells. In this… read more here.
Keywords: atpase; asic3; multiple myeloma; bone ... See more keywords