Long non-coding RNA00882 contributes to platelet-derived growth factor-induced proliferation of human fetal airway smooth muscle cells by enhancing Wnt/β-catenin signaling via sponging miR-3619-5p.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.04.106
Abstract: Long non-coding RNAs (lncRNAs) are emerging as novel and critical regulators in the pathogenesis of asthma. However, the precise role of lncRNAs in pediatric asthma remains largely unknown. In this study, we aimed to investigate… read more here.
Keywords: catenin signaling; asm cells; proliferation; mir 3619 ... See more keywords
TRIP6 accelerates the proliferation and migration of fetal airway smooth muscle cells by enhancing YAP activation.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106366
Abstract: The thyroid receptor interactor protein 6 (TRIP6) has emerged as a key regulator for the proliferation and migration of various cells. However, whether TRIP6 is involved in regulating the proliferation and migration of airway smooth… read more here.
Keywords: proliferation migration; migration fetal; asm cells; migration ... See more keywords
TNFa regulates mitochondrial biogenesis via CREB phosphorylation in human airway smooth muscle
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5732514
Abstract: Airway inflammation is the central driver behind the pathogenesis of respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis, and the very recent pandemic outbreak of COVID-19. Previous studies reported that proinflammatory… read more here.
Keywords: increased mitochondrial; mitochondrial biogenesis; tnfa; physiology ... See more keywords
RETRACTED ARTICLE: The anti-proliferative and anti-inflammatory response of COPD airway smooth muscle cells to hydrogen sulfide
Sign Up to like & getrecommendations! Published in 2018 at "Respiratory Research"
DOI: 10.1186/s12931-018-0788-x
Abstract: BackbroundCOPD is a common, highly debilitating disease of the airways, primarily caused by smoking. Chronic inflammation and structural remodelling are key pathological features of this disease caused, in part, by the aberrant function of airway… read more here.
Keywords: h2s; asm; asm cells; copd ... See more keywords
Evaluation of contractile phenotype in airway smooth muscle cells isolated from endobronchial biopsy and tissue specimens from horses.
Sign Up to like & getrecommendations! Published in 2017 at "American journal of veterinary research"
DOI: 10.2460/ajvr.78.3.359
Abstract: OBJECTIVE To develop a method to maintain the initial phenotype of airway smooth muscle (ASM) cells isolated from equine endobronchial biopsy specimens in long-term cell culture. SAMPLE Endobronchial tissue specimens (8 to 10/horse) collected from… read more here.
Keywords: phenotype; biopsy; asm cells; contractile phenotype ... See more keywords
Glucocorticoid Insensitivity in Asthma: The Unique Role for Airway Smooth Muscle Cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23168966
Abstract: Although most patients with asthma symptoms are well controlled by inhaled glucocorticoids (GCs), a subgroup of patients suffering from severe asthma respond poorly to GC therapy. Such GC insensitivity (GCI) represents a profound challenge in… read more here.
Keywords: role; insensitivity; asthma; asm cells ... See more keywords