Can GPCRs Be Targeted to Control Inflammation in Asthma?
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-68748-9_1
Abstract: Historically, the drugs used to manage obstructive lung diseases (OLDs), asthma, and chronic obstructive pulmonary disease (COPD) either (1) directly regulate airway contraction by blocking or relaxing airway smooth muscle (ASM) contraction or (2) indirectly… read more here.
Keywords: asm; gpcrs targeted; asm contraction; inflammation ... See more keywords
S100A8 protein attenuates airway hyperresponsiveness by suppressing the contraction of airway smooth muscle.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.01.033
Abstract: Airway hyperresponsiveness (AHR) is a major clinical problem in allergic asthma mainly caused by the hypercontractility of airway smooth muscles (ASM). S100A8 is an important member of the S100 calcium-binding protein family with a potential… read more here.
Keywords: asm contraction; airway hyperresponsiveness; contraction; s100a8 protein ... See more keywords