Implementation of the asparaginase activity assessment technique for clinical use: experience of a Brazilian Center
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-78549-y
Abstract: Acute lymphoid leukemia is a childhood cancer that in high-income countries has event-free survival rates of 80% and global survival rates of 90%. In Brazil these rates are under 70%. This difference may be due… read more here.
Keywords: technique; implementation asparaginase; asnase activity; asnase ... See more keywords
Investigating Gut Microbial Taxa and Asparaginase Related Genes in Children Showing Different Direction of Change in Serum Asparaginase Activity Levels during Pegasparaginase Treatment for Acute Lymphoblastic Leukemia
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DOI: 10.1182/blood-2020-142102
Abstract: Background: L-asparaginase (ASNase) converts Asn to Asp and at sustained high levels depletes circulating Asn, leading to leukemic cell death. This dependency has led to the use of ASNase (in a peglyated form, PEGASNase) as… read more here.
Keywords: asnase activity; treatment; asnase; serum asnase ... See more keywords