Gating choreography and mechanism of the human proton-activated chloride channel ASOR
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DOI: 10.1126/sciadv.abm3942
Abstract: The proton-activated chloride channel ASOR (TMEM206/PAC) permeates anions across cellular membranes in response to acidification, thereby enhancing acid-induced cell death and regulating endocytosis. The molecular mechanisms of pH-dependent control are not understood, in part because… read more here.
Keywords: chloride channel; proton activated; asor; activated chloride ... See more keywords