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   Articles with "asp glu" as a keyword



Impact of Asp/Glu-ADP-ribosylation on protein-protein interaction and protein function.

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recommendations! Published in 2022 at "Proteomics"

DOI: 10.1002/pmic.202200083

Abstract: PARylation plays critical roles in regulating multiple cellular processes such as DNA damage response and repair, transcription, RNA processing, and stress response. More than 300 human proteins have been found to be modified by PARylation… read more here.

Keywords: interaction; protein protein; asp glu; parylation ... See more keywords
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Proteins as pH Sensors and Switches

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recommendations! Published in 2017 at "Biophysical Journal"

DOI: 10.1016/j.bpj.2016.11.991

Abstract: Ionizable residues buried in dry or hydrophobic environments in proteins can have extremely anomalous pKa values (pKa > 10 for Asp and Glu, pKa 5 for Lys). These buried ionizable groups are involved in many… read more here.

Keywords: asp glu; pka values; anomalous pka; sensors switches ... See more keywords

Identification of Amino Acid Residues Critical for the Interaction of Fibrin with N-Cadherin.

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recommendations! Published in 2024 at "Biochemistry"

DOI: 10.1021/acs.biochem.4c00510

Abstract: We recently identified N-cadherin as a novel receptor for fibrin and localized complementary binding sites within the fibrin βN-domains and the third and fifth extracellular domains (EC3 and EC5) of N-cadherin. We also hypothesized that… read more here.

Keywords: asp glu; critical interaction; interaction; cadherin ... See more keywords

Ion-Induced Dipole Interactions Matter in Metadynamics Simulation of Transition Metal Ion Transporters

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recommendations! Published in 2025 at "Journal of Chemical Theory and Computation"

DOI: 10.1021/acs.jctc.4c01535

Abstract: Metal transporters play crucial roles in the homeostasis and detoxification of beneficial and toxic metals in the human body. Due to experimental limitations in studying some metal transporters, numerous simulation studies have been conducted to… read more here.

Keywords: transition metal; asp glu; metal; metal asp ... See more keywords