Profile of anti‐herpetic action of ASP2151 (amenamevir) as a helicase‐primase inhibitor
Sign Up to like & getrecommendations! Published in 2017 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2016.12.008
Abstract: &NA; The antiherpetic drugs acyclovir (ACV, valaciclovir) and penciclovir (famciclovir) are phosphorylated by viral thymidine kinase and terminate DNA synthesis. ASP2151 (amenamevir) and foscavir (PFA) directly inhibit viral helicase‐primase and DNA polymerase, respectively, and inhibit… read more here.
Keywords: dna synthesis; dna; asp2151; viral dna ... See more keywords