Articles with "asp3662 novel" as a keyword



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Analgesic effects of ASP3662, a novel 11β‐hydroxysteroid dehydrogenase 1 inhibitor, in rat models of neuropathic and dysfunctional pain

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Published in 2018 at "British Journal of Pharmacology"

DOI: 10.1111/bph.14448

Abstract: Glucocorticoids are a major class of stress hormones known to participate in stress‐induced hyperalgesia. Although 11β‐hydroxysteroid dehydrogenase 1 (11β‐HSD1) is a key enzyme in the intracellular regeneration of glucocorticoids in the CNS, its role in… read more here.

Keywords: effects asp3662; dysfunctional pain; neuropathic dysfunctional; asp3662 novel ... See more keywords