Aldehyde-mediated inhibition of asparagine biosynthesis has implications for diabetes and alcoholism
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DOI: 10.1039/d3sc06551k
Abstract: Patients with alcoholism and type 2 diabetes manifest altered metabolism, including elevated aldehyde levels and unusually low asparagine levels. We show that asparagine synthetase B (ASNS), the only human asparagine-forming enzyme, is inhibited by disease-relevant… read more here.
Keywords: asparagine; asparagine levels; mediated inhibition; alcoholism ... See more keywords